Inability to predict cancer risk through mathematical modelling

Perspective article in Science, Vol. 355, Issue 6331, pp. 1266-1267, “Genes, environment, and “bad luck”   Summary of article: Multiple papers have used mathematical modelling to simulate cancer risk profile at the population level with varying success. Specifically, attempts have been made in correlating cancer stem cell division number with cancer risk; however, can we … More Inability to predict cancer risk through mathematical modelling

Standardization of nomenclature in cell biology and biological sciences

The fields of cell biology and biological sciences is awashed with difficult to remember names and abbreviations that do not identify the function of the proteins or their subunits. For example, the FEAR network in the field of cell biology. Thus, I was wondering if some form of standardization could be instituted by the leading … More Standardization of nomenclature in cell biology and biological sciences

Macrophages as delineators of stripe patterns in zebrafish

Perspective article in Science, Vol. 355, Issue 6331, pp. 1258-1259, “Macrophage, a long-distance middlemen”   Summary of article: Macrophages are immune cells that profile for foreign viruses and cells that invade a multicellular organism, but its myriad characteristics and roles in cellular genesis and developmental biology is only beginning to be understood at both a … More Macrophages as delineators of stripe patterns in zebrafish

Understanding Earth’s collection of viruses

Article in Nature, Vol. 536, Issue 7617, pp. 425-430, “Uncovering Earth’s virome”   Summary of article: A vector based metagenomics approach combined with bioinformatics analysis was used to uncover the subset of viruses present on human body surfaces and freshwater habitats. The study’s experiment design does not fit the grandiose nature of the paper’s title. … More Understanding Earth’s collection of viruses

Remaking photosynthesis for increasing crop yield

Feature article in Nature, Vol. 544, Issue 7651, pp. S11-S13, “Solar upgrade”   Summary of article: Crop production could be severely impacted by rising carbon dioxide concentration in the air as well as global warming. Thus, a slew of efforts is underway in major researcher centres around the world, focusing on enhancing photosynthesis for increasing … More Remaking photosynthesis for increasing crop yield

Mechanobiology technology feature

Feature article in Nature, Vol. 544, Issue. 7649, pp. 255-257, “A measure of molecular muscle”   Summary of article: Seeking to understand how mechanical force influence biological processes at the molecular level, mechanobiology has matured as a field since its inception about a decade ago, where pioneering experiments demonstrating the preferential migration of mammalian cells … More Mechanobiology technology feature

Understanding the evolutionary dynamics of phosphorylation with fungal species as model system

Phosphorylation plays important roles in many aspects of cell biology and intra- and intercellular signaling; for example, serving as markers for epigenetic regulation of gene transcription, and more commonly, as a repository of energy for enzymatic and protein function. But, what determines the selection of specific protein sequence motif as sites for inserting a phosphorus … More Understanding the evolutionary dynamics of phosphorylation with fungal species as model system

Transmissible cancer in marine bivalves: Implications for mode of transmission of cancer

With their rapid growth rate and need for nutrition, cancer cells move as they seek new niches for nutrients and space for colony expansion. Thus far, the most well studied invasive mechanism for cancer cells is metastasis, where a cancer cell from a primary tumour migrate, through the bloodstream, to a new site suitable for … More Transmissible cancer in marine bivalves: Implications for mode of transmission of cancer