Bacterial immune system utilized for genome editing

Feature article in Nature, Vol. 541, Issue 7637, pp. 280-282, “CRISPR’s Mysteries”   Summary of article: Used by bacterial and archaeal species for immune surveillance and defence of the cell against viruses, the single cell organism’s immune system, clustered regularly interspaced short palindromic repeats (CRISPR) system has increasingly find use in alternate scenarios, the most … More Bacterial immune system utilized for genome editing

Understanding laser induced removal of surface coating for materials engineering

Article in Nature, Vol. 537, Issue 7618, pp. 84, “Ablation-cooled material removal with ultrafast bursts of pulses”   Summary of article: Laser assisted ablation cooling was shown to be useful for precision removal of surface coating; thereby, opening up its use for modifying the surface characteristics and functionalities of a material. A top-down approach for … More Understanding laser induced removal of surface coating for materials engineering

Science underlying nucleation of biogenic particles

Article in Nature, Vol. 533, Issue 7604, pp. 521, “Ion-induced nucleation of pure biogenic particles”   Summary of article: Nitrate ions are shown to induce formation of aerosols such as those seeded by α-pinene. Biogenic aerosols play important roles in influencing weather events through inducing the formation of clouds. Thus, by understanding their formation mechanisms … More Science underlying nucleation of biogenic particles

Determining the effect of tropical cyclone on sediment transport by river

Article in Nature, Vol. 539, 10 November 2016, pp. 276, “Fluvial sediment supply to a mega-delta reduced by shifting tropical cyclone activity”   Summary of article: Effect of tropical cyclone on sediment transport along the Mekong river was estimated using a combination of hydrological models and sediment flow data. The authors may not be solving … More Determining the effect of tropical cyclone on sediment transport by river

Structural impediments to synthesis of bacterial cell wall

Article in Nature, Vol. 533, Issue 7604, pp. 557-560, “Structural insights into inhibition of lipid I production in bacterial cell wall synthesis”   Summary of article: Using X-ray diffraction, isothermal titration calorimetry and modelling, modes of binding and conformational rearrangement induced by binding of a synthesized inhibitor into a glycosyl transferase class enzyme was studied, … More Structural impediments to synthesis of bacterial cell wall

Global network of standardized telescopes for time domain astronomy

Feature article in Science, Vol. 356, Issue 6337, pp. 476-479, “A global robotic telescope network helps astronomers keep up with the fast-changing sky”   Summary of article: Using standardized telescopes of diameter between 2 meter and 40 centimeters, a global network of automated telescopes lend clarity to distant stars, galaxies and even exoplanets through the … More Global network of standardized telescopes for time domain astronomy

Inability to predict cancer risk through mathematical modelling

Perspective article in Science, Vol. 355, Issue 6331, pp. 1266-1267, “Genes, environment, and “bad luck”   Summary of article: Multiple papers have used mathematical modelling to simulate cancer risk profile at the population level with varying success. Specifically, attempts have been made in correlating cancer stem cell division number with cancer risk; however, can we … More Inability to predict cancer risk through mathematical modelling

Single cell RNA sequencing for understanding the lineage of cancer cells

Article in Nature, Vol. 539, 10 November 2016, pp. 309, “Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma”   Summary of article: Single cell RNA sequencing of cancer cells from human oligodendroglioma reveals hierarchical development pathway in the cancer; thereby, opening up the technique for use in profiling the developmental pathway and lineage traversed … More Single cell RNA sequencing for understanding the lineage of cancer cells

High temperature magnetic topological insulators

Article in Nature, Vol. 533, Issue 7604, pp. 513, “A high temperature ferromagnetic topological insulating phase by proximity coupling”   Summary of article: Bi2Se3 and EuS adatom bilayer was shown to exhibit topological insulating and magnetic properties. Topological insulator is a class of relatively new materials where the properties of the material differs between the … More High temperature magnetic topological insulators

How dust informs climate now, in the past and future

Article in Nature, Vol. 531, 24 March 2016, pp. 493, “The past, present and future of African dust”   Summary of article: An excellent study on calibrating the effect of wind on topography using dust as an indicator of wind speed and wind fields, which yields important information on how African dust affects weather patterns … More How dust informs climate now, in the past and future