Understanding Earth’s collection of viruses

Article in Nature, Vol. 536, Issue 7617, pp. 425-430, “Uncovering Earth’s virome”


Summary of article: A vector based metagenomics approach combined with bioinformatics analysis was used to uncover the subset of viruses present on human body surfaces and freshwater habitats. The study’s experiment design does not fit the grandiose nature of the paper’s title. Additionally, it is close to impossible to determine, with confidence, the collection of all viruses on Earth. Finally, the vector based metagenomics approach also suffer from the deficiency in not enabling many viruses to successfully integrate with the vector for subsequent polymerase chain reaction (PCR) amplification prior to gene sequencing. Thus, the data presented in the paper, while useful, should not be viewed as the definite collection of all viruses present on the studied human body surfaces and freshwater habitats.


Link to original article: http://www.nature.com/nature/journal/v536/n7617/abs/nature19094.html


Category: Interesting scientific articles, biochemistry, microbiology, molecular biology, genomics, cell biology,

Tags: polymerase chain reaction, virome, metagenomics, vector, freshwater habitats, human body surfaces,


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